Description

2,5-Bis(Trimethylsilyl)-1,4-Phenylene Bis(Trifluoromethanesulfonate) is a highly reactive and versatile organosilicon building block and electrophile. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex aromatic systems. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those requiring functionalized aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with tailored properties.
• Advanced Materials: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Building Block: Provides a protected, reactive phenylene unit for the stepwise construction of complex molecular architectures in research and development.
• Ligand and Catalyst Development: Used to synthesize novel phosphine or nitrogen-based ligands for catalytic systems.

Basic Information

Product Name	2,5-Bis(Trimethylsilyl)-1,4-Phenylene Bis(Trifluoromethanesulfonate)
CAS No.	613676-07-6
Molecular Formula	C14H20F6O6S2Si2
Molecular Weight	526.61 g/mol
Synonyms	1,4-Bis(trifluoromethanesulfonyloxy)-2,5-bis(trimethylsilyl)benzene; 2,5-Bis(trimethylsilyl)-1,4-phenylene ditriflate; 2,5-Bis(trimethylsilyl)benzene-1,4-diyl bis(trifluoromethanesulfonate); 1,4-Bis[(trifluoromethyl)sulfonyloxy]-2,5-bis(trimethylsilyl)benzene; 2,5-Bis(TMS)-1,4-phenylene bis(triflate); 2,5-Bis(trimethylsilyl)-1,4-di(triflyloxy)benzene
EINECS	Contact for details

Quality Control

Our 2,5-Bis(Trimethylsilyl)-1,4-Phenylene Bis(Trifluoromethanesulfonate) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (HPLC/NMR), identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.