Description

2-Picoline-5-Boronic Acid Pinacolate is a high-value organoboron building block, specifically a protected boronic acid derivative. This compound is critical for enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are foundational to modern pharmaceutical and advanced material synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and metal-organic frameworks (MOFs) for catalytic applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Picoline-5-Boronic Acid Pinacolate
CAS No.	610768-32-6
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-picoline; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Picoline-5-boronic acid pinacol ester; 5-(2-Methylpyridinyl)boronic acid pinacol ester; 2-Methyl-5-pyridineboronic acid pinacol ester; 5-Borono-2-picoline pinacol ester; 2-Picolin-5-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Picoline-5-Boronic Acid Pinacolate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.