Description

(E)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Propen-1-Ol is a high-value, protected boronic ester derivative featuring a terminal alcohol functional group. This compound matters as a versatile and stable synthetic intermediate, enabling precise carbon-carbon bond formation in complex molecule assembly. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific boronic acid precursors.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the synthesis of bioconjugates and molecular probes for studying biological processes.
• Custom Fine Chemical Synthesis: A critical reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(E)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Propen-1-Ol
CAS No.	608534-39-0
Molecular Formula	C9H17BO3
Molecular Weight	184.04 g/mol
Synonyms	2-Propen-1-ol, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, (E)-; (E)-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)allyl alcohol; (E)-Allylboronic acid pinacol ester alcohol; trans-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)prop-2-en-1-ol; Pinacol (E)-3-hydroxyprop-1-en-1-ylboronate; (E)-3-Hydroxyprop-1-en-1-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our (E)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Propen-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C for prolonged shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0% (Typical 97-99%)
Isomeric Purity (E/Z ratio by GC/HPLC)	≥98:2 (E:Z)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.