Description

3,4-Pyrrolidinediol, 2-[(4-Methoxyphenyl)Methyl]-, (2R,3R,4S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral pyrrolidine derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology: Serves as a scaffold for developing enzyme inhibitors or molecular probes.
• Process Chemistry: Investigated for scalable synthesis routes in Active Pharmaceutical Ingredient (API) manufacturing.
• Academic Research: Utilized in organic chemistry laboratories for methodological development and teaching advanced synthetic techniques.

Basic Information

Product Name	3,4-Pyrrolidinediol, 2-[(4-Methoxyphenyl)Methyl]-, (2R,3R,4S)-Rel- (9Ci)
CAS No.	604789-40-4
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	rel-(2R,3R,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol; (2R,3R,4S)-2-(4-Methoxybenzyl)pyrrolidine-3,4-diol; 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol, (2R,3R,4S)-rel-; (2R,3R,4S)-rel-2-(4-Methoxybenzyl)pyrrolidine-3,4-diol; 604789-40-4; Pyrrolidine-3,4-diol, 2-[(4-methoxyphenyl)methyl]-, (2R,3R,4S)-rel-
EINECS	Contact for details

Quality Control

Our high-purity chiral intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral HPLC to confirm stereochemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.