Description

4-(Methanesulfonyl)Phenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-sulfonyl functional groups.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Chemical Biology & Proteomics: Useful as a molecular probe or linker in bioconjugation and the development of enzyme inhibitors.
• Catalyst Ligand Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CMOs (Contract Manufacturing Organizations) for client-specific projects.

Basic Information

Product Name	4-(Methanesulfonyl)Phenylboronic Acid Pinacol Ester
CAS No.	603143-27-7
Molecular Formula	C14H21BO4S
Molecular Weight	296.19 g/mol
Synonyms	4-(Methylsulfonyl)phenylboronic acid pinacol ester; [4-(Methanesulfonyl)phenyl]boronic acid pinacol ester; Pinacol [4-(methylsulfonyl)phenyl]boronate; 4-(Methylsulphonyl)phenylboronic acid pinacol ester; B-[4-(Methylsulfonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Methanesulfonyl)benzeneboronic acid pinacol ester; 603143-27-7; 4-Methanesulfonylphenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(Methanesulfonyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistent quality and reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.