Description

(3-Chloro-4-Methoxycarbonyl)Benzeneboronic Acid is a high-purity, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a chloro and an ester substituent on the aromatic ring, enabling precise cross-coupling and subsequent transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its structural motifs to enhance biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, such as polymers for OLEDs and sensors.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and inhibitors that target specific enzymes or biological pathways.
• Ligand Synthesis for Catalysis: Acts as a starting material for constructing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Custom Synthesis & Contract Manufacturing: A vital raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(3-Chloro-4-Methoxycarbonyl)Benzeneboronic Acid
CAS No.	603122-82-3
Molecular Formula	C9H10BClO4
Molecular Weight	228.44 g/mol
Synonyms	3-Chloro-4-(methoxycarbonyl)benzeneboronic acid; (3-Chloro-4-methoxycarbonylphenyl)boronic acid; Methyl 3-chloro-4-boronobenzoate; 4-Borono-3-chlorobenzoic acid methyl ester; Benzeneboronic acid, 3-chloro-4-(methoxycarbonyl)-; 3-Chloro-4-carbomethoxybenzeneboronic acid; 603122-82-3; Methyl 4-borono-3-chlorobenzoate
EINECS	Contact for details

Quality Control

Our (3-Chloro-4-Methoxycarbonyl)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in sensitive applications like pharmaceutical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.