Description

3'-Fluoro-Biphenyl-3-Methanamine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where the fluorine atom and biphenyl scaffold impart desirable biological and physicochemical properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Ligand & Catalyst Design: Utilized in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3'-Fluoro-Biphenyl-3-Methanamine
CAS No.	600735-64-6
Molecular Formula	C13H12FN
Molecular Weight	201.24 g/mol
Synonyms	[3-(3-Fluorophenyl)phenyl]methanamine; 1-(3-Aminomethylphenyl)-3-fluorobenzene; 3'-(Aminomethyl)-3-fluorobiphenyl; 3-(3-Fluorobiphenyl-3-yl)methanamine; (3'-Fluoro[1,1'-biphenyl]-3-yl)methanamine; 3-Fluoro-3'-aminomethylbiphenyl; Biphenyl-3-methanamine, 3'-fluoro-; 3-Aminomethyl-3'-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-Biphenyl-3-Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.