Description

Cyclohexanecarboxaldehyde, 2-Hydroxy-2-Methyl-, (1S,2S)- (9Ci) is a high-purity, chiral aldehyde derivative of cyclohexane, serving as a critical chiral building block in advanced organic synthesis. Its defined stereochemistry at the 1 and 2 positions makes it an indispensable intermediate for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in the development of new asymmetric catalytic reactions and chiral auxiliaries.
• Fine Chemical Production: Serves as a building block for high-value specialty chemicals, including flavors, fragrances, and advanced materials with specific optical properties.
• Academic & Industrial Research: Utilized in methodological studies and process chemistry for constructing complex, stereodefined cyclohexane frameworks.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 2-Hydroxy-2-Methyl-, (1S,2S)- (9Ci)
CAS No.	600726-44-1
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(1S,2S)-2-Hydroxy-2-methylcyclohexanecarboxaldehyde; (1S,2S)-2-Hydroxy-2-methyl-1-cyclohexanecarbaldehyde; (1S,2S)-2-Methyl-2-hydroxycyclohexanecarbaldehyde; (1S,2S)-2-Hydroxy-2-methylcyclohexane-1-carbaldehyde; Chiral 2-Hydroxy-2-methylcyclohexanecarboxaldehyde; (1S,2S)-Aldehyde derivative
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxaldehyde, 2-Hydroxy-2-Methyl-, (1S,2S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.