Description

(2E,4E)-2-[(R)-1-Hydroxy-2-Oxopropyl]-2,4-Hexadienal is a specialized chiral aldehyde derivative with a conjugated diene system, serving as a valuable building block in advanced organic synthesis. Its unique structure, featuring both aldehyde and α-hydroxy ketone functionalities, makes it a versatile precursor for synthesizing complex molecules with precise stereochemistry. This compound is particularly relevant for research and development chemists in the pharmaceutical and fine chemical industries, where it is used to create novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those requiring specific stereocenters and conjugated systems.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, flavors, and fragrances where its dienal structure contributes to specific molecular architectures.
• Agrochemical Research: Employed as a building block for developing novel active ingredients with targeted biological activity.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry, including studies on asymmetric synthesis and cycloaddition reactions.
• Material Science Precursor: Potential use in synthesizing organic ligands or monomers for advanced polymeric materials.

Basic Information

Product Name	(2E,4E)-2-[(R)-1-Hydroxy-2-Oxopropyl]-2,4-Hexadienal
CAS No.	69962-81-8
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	(R)-2-[(1E,3E)-1,3-Hexadien-1-yl]-2-hydroxy-3-oxobutanal; 2,4-Hexadienal, 2-(1-hydroxy-2-oxopropyl)-, (2E,4E)-; (R)-2-Hydroxy-3-oxo-2-[(1E,3E)-1,3-hexadien-1-yl]butanal; (2E,4E)-2-[(1R)-1-Hydroxy-2-oxopropyl]-2,4-hexadienal; Chiral Dienal Synthon; α-Hydroxy-β-keto Dienal
EINECS	Contact for details

Quality Control

Our (2E,4E)-2-[(R)-1-Hydroxy-2-Oxopropyl]-2,4-Hexadienal is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.