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2,6-Dichlorophenylboronic Acid Pinacol Ester CAS NO 69807-92-7


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CAS No.:69807-92-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,6-Dichlorophenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecules. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing biaryl or heterobiaryl scaffolds.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific chlorinated phenyl structures.
  • Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, where its structural motif can influence charge transport.
  • Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
  • Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
  • Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific boronate ester.

Basic Information

Product Name 2,6-Dichlorophenylboronic Acid Pinacol Ester
CAS No. 69807-92-7
Molecular Formula C12H15BCl2O2
Molecular Weight 273.96 g/mol
Synonyms 2,6-Dichlorophenylboronic Acid Pinacol Ester; 2,6-Dichlorophenylboronic Acid Pinanediol Ester (common alternative); 4,4,5,5-Tetramethyl-2-(2,6-dichlorophenyl)-1,3,2-dioxaborolane; (2,6-Dichlorophenyl)boronic Acid Pinacol Ester; Pinacol (2,6-Dichlorophenyl)boronate; 2-(2,6-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-(2,6-dichlorophenyl)-, 1,1-dimethylethyl ester (related); 69807-92-7 (CAS Index Name).
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Quality Control

Our 2,6-Dichlorophenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including research and cGMP-grade material for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when weighing to prevent hydrolysis and maintain reactivity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤0.5%
Melting Point Contact for details
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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