Description

3-Hydroxy-2,2-Dimethyl-Butyric Acid Ethyl Ester is a valuable chiral building block and intermediate in organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in statin-class drugs and other therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its branched-chain structure.
• Flavor & Fragrance Ingredient: Serves as a precursor for esters and lactones that contribute to fruity and creamy flavor notes.
• Polymer Modification: Acts as a monomer or co-monomer for introducing hydroxy-functional groups into specialty polymers.
• Organic Synthesis Reagent: Employed in asymmetric synthesis, Grignard reactions, and as a protected form of 3-hydroxy-2,2-dimethylbutyric acid.
• Liquid Crystal & Electronic Materials: Intermediate in the synthesis of advanced organic materials for electronic applications.

Basic Information

Product Name	3-Hydroxy-2,2-Dimethyl-Butyric Acid Ethyl Ester
CAS No.	69737-23-1
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	Ethyl 3-Hydroxy-2,2-Dimethylbutyrate; 2,2-Dimethyl-3-hydroxybutyric Acid Ethyl Ester; 3-Hydroxy-2,2-dimethylbutanoic Acid Ethyl Ester; Ethyl 3-Hydroxy-2,2-dimethylbutanoate; HDMB Ethyl Ester; 69737-23-1; Butanoic acid, 3-hydroxy-2,2-dimethyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2,2-Dimethyl-Butyric Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.