Description

1-[[(Chloromethyl)Sulfonyl]Methyl]-4-Nitrobenzene is a specialized organic intermediate featuring a reactive chloromethyl sulfonyl group adjacent to a nitro-substituted benzene ring. This unique bifunctional structure makes it a valuable building block for synthesizing more complex molecules in advanced chemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel sulfonamide-based drug candidates, potentially for enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, leveraging the reactivity of the chloromethyl and sulfonyl groups.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, coatings, or functional materials with specific sulfone linkages.
• Chemical Biology Probes: Employed in the creation of molecular probes or affinity labels for studying biological processes due to its electrophilic chloromethyl moiety.
• Ligand and Catalyst Development: Utilized as a starting material for constructing complex chelating ligands or organocatalysts in asymmetric synthesis.

Basic Information

Product Name	1-[[(Chloromethyl)Sulfonyl]Methyl]-4-Nitrobenzene
CAS No.	69688-53-5
Molecular Formula	C8H8ClNO4S
Molecular Weight	249.67 g/mol
Synonyms	4-Nitrobenzyl chloromethyl sulfone; 1-(Chloromethylsulfonylmethyl)-4-nitrobenzene; (4-Nitrobenzyl) chloromethyl sulfone; α-(Chloromethylsulfonyl)-4-nitrotoluene; p-Nitrobenzyl chloromethyl sulfone; Benzene, 1-[[(chloromethyl)sulfonyl]methyl]-4-nitro-; NSC 403119
EINECS	Contact for details

Quality Control

Our 1-[[(Chloromethyl)Sulfonyl]Methyl]-4-Nitrobenzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.