Description

2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Xylopyranose 1-Phosphoric Acid Bis(Trimethylsilyl) Ester is a highly functionalized, silyl-protected carbohydrate derivative that serves as a critical synthetic intermediate. This compound is valued for its role in facilitating complex organic syntheses, particularly in the preparation of nucleoside analogs and other bioactive molecules where precise stereochemistry and protecting group strategies are paramount. It is primarily utilized by research institutions and pharmaceutical development teams engaged in advanced carbohydrate chemistry and medicinal chemistry programs.

Application

• Synthetic Intermediate for Nucleoside Analogs: A key building block in the synthesis of modified nucleosides with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions and protecting group methodologies.
• Pharmaceutical Development: Serves as a precursor in the development of novel therapeutic agents, including prodrugs and diagnostic agents.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified sugars for probing biological pathways and enzyme mechanisms.
• Oligosaccharide Synthesis: Acts as a protected xylose donor or acceptor in the stepwise construction of complex oligosaccharides.

Basic Information

Product Name	2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Xylopyranose 1-Phosphoric Acid Bis(Trimethylsilyl) Ester
CAS No.	69688-47-7
Molecular Formula	C20H51O9PSi5
Molecular Weight	619.03 g/mol
Synonyms	D-Xylopyranose, 2,3,4-tris-O-(trimethylsilyl)-, 1-(bis(trimethylsilyl) phosphate); 1-Phosphoric Acid Bis(Trimethylsilyl) Ester of 2,3,4-Tris-O-(trimethylsilyl)-D-xylopyranose; Tris(trimethylsilyl) D-xylopyranosyl phosphate bis(trimethylsilyl) ester; Silylated D-Xylose Phosphate Ester; Protected Xylose Phosphate; TMS-Xylose Phosphate
EINECS	Contact for details

Quality Control

Our production of this advanced synthetic intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is characterized using advanced analytical techniques, including NMR (¹H, ¹³C, ³¹P) and HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.