Description

2-Chloro-1-(4-Methylphenyl)-1-Propanone is a specialized organic intermediate featuring a chlorinated propanone backbone attached to a methyl-substituted phenyl ring. This compound matters for its role as a crucial building block in the synthesis of more complex molecules, particularly in fine chemical and pharmaceutical research. Industries that require this chemical include pharmaceutical R&D for active pharmaceutical ingredient (API) synthesis, agrochemical manufacturing for crop protection agents, and academic laboratories engaged in organic methodology development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with aryl ketone or phenethylamine structural motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require a halogenated aryl ketone moiety.
• Fine Chemical Manufacturing: Serves as a versatile building block for creating complex molecules used in dyes, pigments, and specialty polymers.
• Organic Synthesis Research: Employed in academic and industrial R&D for developing new carbon-carbon bond-forming reactions, such as Friedel-Crafts acylation or nucleophilic substitution studies.
• Material Science Precursor: Potential use in the synthesis of monomers or ligands for advanced materials, including liquid crystals or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Chloro-1-(4-Methylphenyl)-1-Propanone
CAS No.	69673-92-3
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	2-Chloro-1-(p-tolyl)propan-1-one; 2-Chloro-1-(4-methylphenyl)propan-1-one; p-Methyl-2-chloropropiophenone; 1-Propanone, 2-chloro-1-(4-methylphenyl)-; 4'-Methyl-2-chloropropiophenone; α-Chloro-p-methylpropiophenone; 2-Chloro-1-(4-methylphenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(4-Methylphenyl)-1-Propanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.