Description

E-Crotylboronic Acid Pinacol Ester, trans-2-(2-Buten-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound is valued for its stability and reactivity, serving as a key reagent in the formation of carbon-carbon bonds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for palladium-catalyzed cross-couplings to introduce the crotyl (2-butenyl) moiety into aromatic and heteroaromatic systems.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), particularly for creating chiral centers and olefinic side chains.
• Agrochemical Active Ingredient Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific alkene functionalities.
• Material Science & Polymer Chemistry: Acts as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Natural Product & Fine Chemical Synthesis: Facilitates the stereoselective construction of complex natural products and high-value fine chemicals in research laboratories.
• Process Chemistry & Scale-up: Provides a reliable and consistent boronic ester for transition from laboratory-scale discovery to pilot and commercial-scale manufacturing.

Basic Information

Product Name	E-Crotylboronic Acid Pinacol Ester, trans-2-(2-Buten-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	69611-02-5
Molecular Formula	C10H19BO2
Molecular Weight	182.07 g/mol
Synonyms	trans-Crotylboronic Acid Pinacol Ester; (E)-2-Buten-1-ylboronic Acid Pinacol Ester; (E)-CrotylPinacolborane; trans-2-Buten-1-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-1-Buten-3-ylboronic Acid Pinacol Ester; Pinacol (E)-Crotylboronate; (E)-CrotylBPin; B-(trans-2-Butenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our E-Crotylboronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot undergoes comprehensive analytical testing, including NMR, GC, and HPLC analysis, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with full specification data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when dispensing from the original container to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (NMR)	≥ 95.0%
Isomeric Purity (E/Z ratio by GC)	≥ 98:2
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.