Description

Z-2-Buten-1-Yl-Boronic Acid Pinacol Ester, Z-Crotylboronic Acid Pinacol Ester, cis-2-(2-Buten-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron reagent prized for its stereochemical integrity and reactivity. This compound is a crucial building block in modern synthetic chemistry, enabling the stereoselective formation of carbon-carbon bonds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Stereoselective Allylation Reactions: Key reagent for the stereocontrolled addition of a crotyl group to aldehydes and ketones, forming homoallylic alcohols with defined geometry.
• Pharmaceutical Intermediate Synthesis: Used in the construction of chiral centers and carbon skeletons for active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Active Ingredient Development: Employed in the synthesis of complex, bioactive molecules for crop protection and pest management.
• Natural Product and Fine Chemical Synthesis: Facilitates the efficient and selective synthesis of complex natural products and specialty chemicals.
• Material Science Research: Serves as a precursor for introducing functional organic groups into polymers or advanced organic materials.
• Cross-Coupling Reactions: Can be utilized as a boronic ester partner in Suzuki-Miyaura cross-coupling reactions to form new C-C bonds.

Basic Information

Product Name	Z-2-Buten-1-Yl-Boronic Acid Pinacol Ester
CAS No.	69611-01-4
Molecular Formula	C₁₀H₁₉BO₂
Molecular Weight	182.07 g/mol
Synonyms	Z-Crotylboronic Acid Pinacol Ester; cis-2-(2-Buten-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane; (Z)-2-Buten-1-ylboronic Acid Pinacol Ester; (Z)-Crotylpinacolborane; (Z)-2-Butenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (Z)-crotylboronate; (Z)-1-Buten-3-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Z-Crotylboronic Acid Pinacol Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity, essential for sensitive synthetic applications. All products undergo rigorous analytical testing, including NMR, GC, and HPLC analysis, to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Isomeric Purity (Z-isomer)	≥ 95.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.