Description

(Z)-12-(Tetrahydro-2H-Pyran-2-Yloxy)-3-Dodecene-1-Ol is a high-value, protected alcohol intermediate featuring a specific stereochemistry and a tetrahydropyranyl (THP) ether protecting group. This compound matters for its role as a versatile chiral building block in complex organic synthesis, enabling the controlled introduction of functional groups. It is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the production of advanced active pharmaceutical ingredients (APIs), fragrances, and liquid crystal materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, leukotrienes, and other bioactive molecules with specific stereochemical requirements.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, flavors, and fragrances where the THP group offers orthogonal protection strategies.
• Material Science Research: Serves as a precursor for monomers or ligands in the development of specialized polymers and liquid crystalline compounds.
• Academic & R&D Laboratories: Employed in methodological studies and the development of new asymmetric synthesis routes and catalytic processes.
• Process Chemistry: Evaluated for scale-up in the production of high-value target molecules under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	(Z)-12-(Tetrahydro-2H-Pyran-2-Yloxy)-3-Dodecene-1-Ol
CAS No.	69494-16-2
Molecular Formula	C₁₇H₃₂O₃
Molecular Weight	284.43 g/mol
Synonyms	(Z)-12-(Tetrahydro-2H-pyran-2-yloxy)-3-dodecen-1-ol; 3-Dodecene-1-ol, 12-(tetrahydro-2H-pyran-2-yloxy)-, (Z)-; (Z)-12-(THP-Oxy)-3-dodecene-1-ol; THP-protected (Z)-12-hydroxy-3-dodecen-1-ol; (Z)-12-(Tetrahydropyran-2-yloxy)dodec-3-en-1-ol; (3Z)-12-(Oxan-2-yloxy)dodec-3-en-1-ol; Protected (Z)-Unsaturated Alcohol Intermediate
EINECS	Contact for details

Quality Control

Our (Z)-12-(Tetrahydro-2H-Pyran-2-Yloxy)-3-Dodecene-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be kept separate from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (Z-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.