Description

2-(tert-Butyldimethylsiloxy)Pent-2-En-4-One is a high-purity, protected enone building block widely used in advanced organic synthesis. This compound is valued for its role as a key chiral intermediate in the production of complex pharmaceutical molecules and fine chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing intricate molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in prostaglandin and steroid analog pathways.
• Asymmetric Synthesis: Serves as a versatile substrate in stereoselective reactions, including Michael additions and aldol condensations, to introduce chiral centers.
• Natural Product Synthesis: Used in the total synthesis of complex natural products requiring specific enone functionalities with protective group chemistry.
• Agrochemical Research: Employed as a building block for developing novel pesticides and herbicides with targeted biological activity.
• Material Science Precursor: Acts as an intermediate for synthesizing specialized monomers or ligands used in catalyst design and advanced polymers.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of high-value fine chemicals.

Basic Information

Product Name	2-(tert-Butyldimethylsiloxy)Pent-2-En-4-One
CAS No.	69404-97-3
Molecular Formula	C11H22O2Si
Molecular Weight	214.38 g/mol
Synonyms	2-[(tert-Butyldimethylsilyl)oxy]pent-2-en-4-one; 2-(TBDMSO)Pent-2-En-4-One; 4-Penten-2-one, 2-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 2-(tert-Butyldimethylsilyloxy)-2-penten-4-one; 2-(Tert-butyldimethylsiloxy)-2-penten-4-one; 2-(TBDMS-Oxy)-2-penten-4-one; Protected 2-Hydroxypenten-4-one; TBDMS enol ether of acetylacetone
EINECS	Contact for details

Quality Control

Our 2-(tert-Butyldimethylsiloxy)Pent-2-En-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.