Description

(3R)-4,4A,5,6,7,8-Hexahydro-3α,4Aβ-Dihydroxy-4β-Methyl-6α-(1-Methylethenyl)Naphthalen-2(3H)-One is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex polycyclic structure with specific hydroxyl and ketone functionalities makes it a valuable chiral building block for the development of novel bioactive compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in complex molecule construction and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex natural product derivatives.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides where specific spatial orientation is critical for bioactivity.
• Organic Synthesis Research: Serves as a sophisticated starting material or intermediate in academic and industrial laboratories for methodology development and total synthesis projects.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical purity and complex molecular architecture.
• Asymmetric Catalysis Studies: Acts as a substrate or ligand precursor in the development and testing of new asymmetric catalytic systems.

Basic Information

Product Name	(3R)-4,4A,5,6,7,8-Hexahydro-3α,4Aβ-Dihydroxy-4β-Methyl-6α-(1-Methylethenyl)Naphthalen-2(3H)-One
CAS No.	69297-50-3
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	(3R)-4,4a,5,6,7,8-Hexahydro-3α,4aβ-dihydroxy-4β-methyl-6α-isopropenyl-2(3H)-naphthalenone; 6α-Isopropenyl-4β-methyl-4aβ,3α-dihydroxy-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone; (3R,4R,4aS,6R)-4,4a,5,6,7,8-Hexahydro-4-methyl-6-(prop-1-en-2-yl)naphthalene-2,3,4a(3H)-triol; 2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-3,4a-dihydroxy-4-methyl-6-(1-methylethenyl)-, (3R,4R,4aS,6R)-; A key intermediate in forskolin synthesis.
EINECS	Contact for details

Quality Control

Our (3R)-4,4A,5,6,7,8-Hexahydro-3α,4Aβ-Dihydroxy-4β-Methyl-6α-(1-Methylethenyl)Naphthalen-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high stereochemical and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for the grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.