Description

1,1,1-Trifluoro-5-Methoxypentan-2-One is a versatile fluorinated ketone building block, valued for its unique trifluoromethyl group and methoxy-functionalized alkyl chain. This compound is essential for introducing fluorine atoms into target molecules, significantly altering their physicochemical properties such as metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated segments.
• Organic Synthesis Reagent: Employed in various fluorination reactions, Michael additions, and as a precursor for heterocyclic compounds in academic and industrial R&D.
• Fluorine-19 NMR Spectroscopy: Can be utilized as a reference standard or a chemical shift reagent due to its distinct fluorine signature.

Basic Information

Product Name	1,1,1-Trifluoro-5-Methoxypentan-2-One
CAS No.	69243-10-3
Molecular Formula	C7H9F3O2
Molecular Weight	170.14 g/mol
Synonyms	5-Methoxy-1,1,1-trifluoropentan-2-one; 1,1,1-Trifluoro-5-methoxy-2-pentanone; 5-Methoxy-1,1,1-trifluoro-2-pentanone; 2-Pentanone, 1,1,1-trifluoro-5-methoxy-; Trifluoroacetylbutyl methyl ether; 5-Methoxy-1,1,1-trifluoro-pentan-2-one; 69243-10-3
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-5-Methoxypentan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.