Description

A-Trifluoroacetyl-G-Butyrolactone is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value proposition lies in its unique molecular structure, which incorporates both a reactive lactone and a trifluoroacetyl group, enabling the efficient introduction of fluorine atoms into complex molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the introduction of fluorine enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers and advanced materials with tailored surface properties and chemical resistance.
• Fluorine Chemistry Research: An essential reagent in academic and industrial R&D for exploring new fluorination methodologies and creating novel fluoroorganic compounds.
• Ligand and Catalyst Development: Employed in the synthesis of complex, fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	A-Trifluoroacetyl-G-Butyrolactone
CAS No.	69243-04-5
Molecular Formula	C6H5F3O3
Molecular Weight	182.10 g/mol
Synonyms	4-(Trifluoroacetyl)butyrolactone; 4-(Trifluoroacetyl)dihydro-2(3H)-furanone; 2-Oxo-4-(trifluoroacetyl)tetrahydrofuran; α-Trifluoroacetyl-γ-butyrolactone; 3-Oxo-5-(trifluoroacetyl)tetrahydrofuran; 4-Trifluoroacetylbutyrolactone; 4-Trifluoroacetyl-2-butyrolactone; 4-Trifluoroacetyldihydrofuran-2(3H)-one
EINECS	Contact for details

Quality Control

Our A-Trifluoroacetyl-G-Butyrolactone is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.