Description

2-Butyl-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, organoboron reagent widely used as a key intermediate in advanced organic synthesis. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality building blocks for drug discovery, catalyst development, and functional polymer synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific aryl-alkyl linkages.
• Materials Science & Polymer Chemistry: Employed in the creation of novel organic electronic materials, liquid crystals, and functional polymers.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing specialized catalysts and ligands used in homogeneous catalysis.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and complex molecule construction.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	2-Butyl-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	69190-62-1
Molecular Formula	C₁₀H₂₁BO₂
Molecular Weight	184.09 g/mol
Synonyms	2-Butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Butylpinacolborane; n-Butylboronic acid pinacol ester; n-Butyl-Bpin; 1-Butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; n-Butylpinacol boronate; 2-Butyl-2,5,5-trimethyl-1,3,2-dioxaborinane (related structure); B-Butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Butyl-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR, GC, and HPLC analysis, to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.