Description

2-Fluoro-4-Methylbiphenyl is a high-purity fluorinated aromatic compound, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique structure, which combines a biphenyl core with fluorine and methyl substituents, enabling precise modifications to the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), improving performance and longevity.
• Polymer Science: Employed as a monomer or modifier to create specialty polymers with enhanced thermal stability, chemical resistance, and specific optical properties.
• Chemical Research & Development: A versatile reagent in cross-coupling reactions (e.g., Suzuki, Heck) and for introducing fluorinated biphenyl motifs into complex molecular architectures.
• Material Science: Investigated for use in organic semiconductors and other electronic materials due to its favorable charge transport characteristics.

Basic Information

Product Name	2-Fluoro-4-Methylbiphenyl
CAS No.	69168-29-2
Molecular Formula	C13H11F
Molecular Weight	186.23 g/mol
Synonyms	2-Fluoro-4-methyl-1,1'-biphenyl; 4'-Methyl-2-fluorobiphenyl; 1-Fluoro-2-(4-methylphenyl)benzene; (2-Fluoro-4-methylphenyl)benzene; Biphenyl, 2-fluoro-4-methyl-; 2-Fluoro-4'-methylbiphenyl
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Methylbiphenyl is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.