Description

1-Benzylhexahydro-1H-Cyclopenta[B]Pyridin-4(4Ah)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused bicyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of high-value specialty chemicals seeking reliable and consistent quality for their critical processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Custom Synthesis: Serves as a starting material or intermediate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals beyond pharmaceuticals.
• Chemical Reference Standard: Can be supplied as a certified reference material for analytical method development and quality control.

Basic Information

Product Name	1-Benzylhexahydro-1H-Cyclopenta[B]Pyridin-4(4Ah)-One
CAS No.	69042-25-7
Molecular Formula	C₁₉H₂₅NO
Molecular Weight	283.41 g/mol
Synonyms	1-Benzyl-1,4,4a,5,6,7-hexahydrocyclopenta[b]pyridin-4-one; 1-Benzyl-4-oxo-1,4,4a,5,6,7-hexahydrocyclopenta[b]pyridine; 4(4aH)-Cyclopenta[b]pyridinone, 1-benzylhexahydro-; 1-Benzylhexahydrocyclopenta[b]pyridin-4-one
EINECS	Contact for details

Quality Control

Our 1-Benzylhexahydro-1H-Cyclopenta[B]Pyridin-4(4Ah)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade materials and stringent regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.