Description

Benzyl(Difluoromethyl)Sulfane is a specialized organosulfur compound featuring a difluoromethylthio group attached to a benzyl moiety. This unique structure makes it a valuable fluorinated building block and intermediate in advanced synthetic chemistry, particularly for introducing the SCF2H group into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, especially in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the difluoromethylthio group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or modifying agent in the development of specialty polymers and advanced materials with tailored surface properties.
• Fluorination Reagent: Acts as a source of the SCF2H moiety in nucleophilic or radical fluorination reactions to create complex fluoroorganic molecules.
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis, where the sulfur and fluorine atoms can modulate electronic properties.
• Chemical Research: A versatile reagent for method development in organic synthesis, enabling new C-S bond forming strategies.

Basic Information

Product Name	Benzyl(Difluoromethyl)Sulfane
CAS No.	68965-44-6
Molecular Formula	C8H8F2S
Molecular Weight	174.21 g/mol
Synonyms	Benzyl difluoromethyl sulfide; (Difluoromethylsulfanyl)methylbenzene; α-(Difluoromethylthio)toluene; S-(Difluoromethyl) benzothioate; Benzyl S-difluoromethyl thioether; 1-(Difluoromethylthio)methylbenzene; Toluene, α-(difluoromethylthio)-; Benzylthiomethyl difluoride
EINECS	Contact for details

Quality Control

Our Benzyl(Difluoromethyl)Sulfane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong alkali and fluoride ions; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.