Description

2,3,4-Trimethoxyphenylacetonitrile is a versatile and high-value aromatic nitrile building block characterized by its unique substitution pattern. This compound matters as a critical synthetic intermediate for constructing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for applications such as the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring a multi-methoxylated phenyl core.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: A starting material in the synthesis of advanced organic semiconductors and charge-transport materials.
• Dye and Pigment Intermediate: Employed in the production of specialized dyes and functional pigments.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2,3,4-Trimethoxyphenylacetonitrile
CAS No.	68913-85-9
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	(2,3,4-Trimethoxyphenyl)acetonitrile; 2-(2,3,4-Trimethoxyphenyl)acetonitrile; 2,3,4-Trimethoxybenzyl cyanide; α-Cyano-2,3,4-trimethoxytoluene; 2,3,4-Trimethoxybenzeneacetonitrile; 2,3,4-Trimethoxyphenyl cyanomethyl; 68913-85-9 (CAS)
EINECS	Contact for details

Quality Control

Our 2,3,4-Trimethoxyphenylacetonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality systems are designed to support cGMP requirements for pharmaceutical development, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.