Description

(S)-3-Phenyl-4-Hydroxybutyric Acid 1,4-Lactone CAS NO 68844-05-3 is a high-purity chiral lactone building block of significant synthetic utility. Its value lies in its stereochemically defined structure, which is crucial for imparting specific biological activity in advanced pharmaceutical intermediates. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly those targeting the central nervous system (CNS) and cardiovascular diseases.
• Asymmetric Synthesis: Serves as a versatile starting material or precursor for constructing complex molecular architectures via stereoselective reactions.
• Natural Product Synthesis: Used in the laboratory-scale synthesis of natural products and their analogs that contain chiral γ-lactone or phenyl-substituted motifs.
• Agrochemical Research: Potential building block for developing novel, chiral active ingredients with improved efficacy and selectivity.
• Material Science Precursor: Can be utilized in the research and development of specialty polymers or liquid crystals where chirality influences material properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or biological pathways.

Basic Information

Product Name	(S)-3-Phenyl-4-Hydroxybutyric Acid 1,4-Lactone
CAS No.	68844-05-3
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	(S)-3-Phenyl-γ-butyrolactone; (S)-3-Phenyl-4-butanolide; (S)-3-Phenyldihydro-2(3H)-furanone; (S)-3-Phenyl-γ-lactone; (S)-3-Phenyl-4-hydroxybutanoic acid lactone; (S)-3-Phenyl-4-hydroxybutyric acid γ-lactone; (S)-3-Phenyltetrahydro-2-furanone; (S)-3-Phenyl-2-oxolanone
EINECS	Contact for details

Quality Control

Our (S)-3-Phenyl-4-Hydroxybutyric Acid 1,4-Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.