Description

2-(1-Naphthylene)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity organoboron reagent, specifically a naphthalene-derived boronic ester pinacol ester. This compound is a critical synthetic intermediate valued for its stability and reactivity in cross-coupling reactions, enabling the efficient construction of complex organic frameworks. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery, ligand synthesis, and the development of organic electronic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between the naphthyl group and aryl/heteroaryl halides, fundamental in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates containing naphthalene scaffolds.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science & Organic Electronics: A precursor for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile tool for academic and industrial R&D in synthetic organic chemistry.

Basic Information

Product Name	2-(1-Naphthylene)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	68716-52-9
Molecular Formula	C₁₈H₂₁BO₂
Molecular Weight	280.17 g/mol
Synonyms	1-Naphthaleneboronic Acid Pinacol Ester; 1-Naphthylboronic Acid Pinacol Ester; (1-Naphthyl)Pinacolboronate; 1-NaphthylBPin; 1-Naphthalenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Naphthylboronic Acid, Pinacol Ester; 1-Naphthyl-Bpin; 1-Naphthaleneboronic Acid, Cyclic Ester with Pinacol
EINECS	Contact for details

Quality Control

Our 2-(1-Naphthylene)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.