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2,4-Dichlorophenylboronic Acid, Pinacol Ester CAS NO 68716-50-7
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CAS No.:68716-50-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,4-Dichlorophenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its enhanced stability and handling properties compared to the free boronic acid, making it an indispensable reagent for Suzuki-Miyaura cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, consistent performance in constructing complex biaryl and heterobiaryl structures.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
- Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides containing the 2,4-dichlorophenyl moiety.
- Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
- Material Science Research: Building block for creating organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
- Chemical Biology Probes: Utilized in the development of molecular probes and tags for biochemical research.
- Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving diverse R&D and scale-up projects.
Basic Information
| Product Name | 2,4-Dichlorophenylboronic Acid, Pinacol Ester |
| CAS No. | 68716-50-7 |
| Molecular Formula | C12H15BCl2O2 |
| Molecular Weight | 273.96 g/mol |
| Synonyms | 2,4-Dichlorophenylboronic Acid Pinacol Ester; 2,4-Dichlorophenylboronic Acid Pinanediol Ester (common trade name context); 4,4,5,5-Tetramethyl-2-(2,4-dichlorophenyl)-1,3,2-dioxaborolane; (2,4-Dichlorophenyl)boronic Acid Pinacol Ester; Pinacol (2,4-Dichlorophenyl)boronate; 2-(2,4-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(2,4-Dichlorophenyl)boronic Acid Pinacol Ester |
| EINECS | Contact for details |
Quality Control
Every batch of our 2,4-Dichlorophenylboronic Acid, Pinacol Ester is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible cross-coupling yields. Comprehensive analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Purity (GC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 10 ppm |
| Residual Solvents | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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