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2,4-Dichlorophenylboronic Acid, Pinacol Ester CAS NO 68716-50-7


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CAS No.:68716-50-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4-Dichlorophenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its enhanced stability and handling properties compared to the free boronic acid, making it an indispensable reagent for Suzuki-Miyaura cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, consistent performance in constructing complex biaryl and heterobiaryl structures.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
  • Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides containing the 2,4-dichlorophenyl moiety.
  • Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
  • Material Science Research: Building block for creating organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
  • Chemical Biology Probes: Utilized in the development of molecular probes and tags for biochemical research.
  • Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving diverse R&D and scale-up projects.

Basic Information

Product Name 2,4-Dichlorophenylboronic Acid, Pinacol Ester
CAS No. 68716-50-7
Molecular Formula C12H15BCl2O2
Molecular Weight 273.96 g/mol
Synonyms 2,4-Dichlorophenylboronic Acid Pinacol Ester; 2,4-Dichlorophenylboronic Acid Pinanediol Ester (common trade name context); 4,4,5,5-Tetramethyl-2-(2,4-dichlorophenyl)-1,3,2-dioxaborolane; (2,4-Dichlorophenyl)boronic Acid Pinacol Ester; Pinacol (2,4-Dichlorophenyl)boronate; 2-(2,4-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(2,4-Dichlorophenyl)boronic Acid Pinacol Ester
EINECS Contact for details

Quality Control

Every batch of our 2,4-Dichlorophenylboronic Acid, Pinacol Ester is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible cross-coupling yields. Comprehensive analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Purity (GC) ≥ 97.0%
Melting Point Contact for details
Heavy Metals < 10 ppm
Residual Solvents Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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