Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Nitrobenzene is a high-purity organoboron building block, specifically a nitro-substituted phenylboronic ester. This compound is a critical intermediate in modern synthetic chemistry, enabling the precise construction of complex molecular architectures through cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific nitro-aromatic scaffolds.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological pathways and target engagement.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Nitrobenzene
CAS No.	68716-48-3
Molecular Formula	C12H16BNO4
Molecular Weight	249.08 g/mol
Synonyms	3-Nitrophenylboronic acid pinacol ester; (3-Nitrophenyl)boronic acid pinacol ester; 3-Nitrobenzeneboronic acid pinacol ester; 3-Nitrophenyl-Bpin; 1-Nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; PINACOL 3-NITROPHENYLBORONATE; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and GC to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.