Description

Ethyl 5-(2-Fluorophenyl)-1,3,4-Oxadiazole-2-Carboxylate is a high-value fluorinated heterocyclic building block, specifically a 1,3,4-oxadiazole derivative, essential for advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecules with potential biological activity, offering chemists a precise handle for structure-activity relationship (SAR) studies. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a building block for synthesizing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the 1,3,4-oxadiazole core.
• Material Science Precursor: Used in the synthesis of specialty polymers and liquid crystals, where the fluorophenyl-oxadiazole unit can impart specific electronic or thermal properties.
• Chemical Biology Probe Development: Employed in creating molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	Ethyl 5-(2-Fluorophenyl)-1,3,4-Oxadiazole-2-Carboxylate
CAS No.	68496-86-6
Molecular Formula	C11H9FN2O3
Molecular Weight	236.20 g/mol
Synonyms	Ethyl 2-fluoro-5-(1,3,4-oxadiazol-2-yl)benzoate; 5-(2-Fluorophenyl)-1,3,4-oxadiazole-2-carboxylic acid ethyl ester; 2-Fluorophenyl-1,3,4-oxadiazole-2-ethyl carboxylate; 1,3,4-Oxadiazole-2-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester; Ethyl 5-(o-fluorophenyl)-1,3,4-oxadiazole-2-carboxylate; 68496-86-6; 2-Fluorophenyl oxadiazole ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(2-Fluorophenyl)-1,3,4-Oxadiazole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.