Description

4-Fluorocyclohexanone is a versatile fluorinated organic building block, a key intermediate in advanced chemical synthesis. Its value lies in the strategic introduction of a fluorine atom into the cyclohexanone scaffold, which can significantly alter the physical, chemical, and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and novel drug candidates, where fluorine substitution can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging fluorine's ability to enhance biological activity and environmental persistence.
• Liquid Crystal & Advanced Material Research: Acts as a building block for fluorinated liquid crystal compounds and specialty polymers, contributing to improved dielectric properties and thermal stability.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for exploring new fluorination methodologies, asymmetric synthesis, and as a substrate for catalyst development.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing fluorinated aroma chemicals, although specific applications require detailed evaluation.

Basic Information

Product Name	4-Fluorocyclohexanone
CAS No.	68223-64-3
Molecular Formula	C6H9FO
Molecular Weight	116.14 g/mol
Synonyms	4-Fluorocyclohexanone; 4-Fluoro-cyclohexanone; Cyclohexanone, 4-fluoro-; 4-Fluorocyclohexan-1-one; 4-Fluoro-1-cyclohexanone; 4-Fluorocyclohexyl ketone; p-Fluorocyclohexanone; 4-FCH
EINECS	Contact for details

Quality Control

Our 4-Fluorocyclohexanone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting key parameters such as assay and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability, although short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Specific Gravity (20°C)	~1.05 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.