Description

Ks-Selectride® is a highly selective and powerful reducing agent, specifically potassium tri-sec-butylborohydride in a 1.0M solution in tetrahydrofuran. This compound is valued for its exceptional ability to perform stereoselective reductions of ketones and aldehydes, offering high yields and predictable outcomes in complex synthetic pathways. It is an essential reagent for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, where precise control over molecular architecture is critical.

Application

• Stereoselective Ketone Reduction: Key for producing specific enantiomers of chiral secondary alcohols, a fundamental step in active pharmaceutical ingredient (API) synthesis.
• Aldehyde Reduction: Efficient conversion of aldehydes to primary alcohols under mild conditions.
• Asymmetric Synthesis: Employed in the construction of complex, optically active molecules for drug discovery and development.
• Process Chemistry: Used in scale-up and manufacturing processes for high-value intermediates where selectivity and reproducibility are paramount.
• Fine Chemical Production: Synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A staple reagent in methodology development and exploratory chemistry for novel compound libraries.

Basic Information

Product Name	Ks-Selectride®
CAS No.	67966-25-0
Molecular Formula	C₁₂H₂₈BK
Molecular Weight	222.27 g/mol
Synonyms	Potassium tri-sec-butylborohydride; Potassium tri(sec-butyl)borohydride; Potassium tri-sec-butylhydroborate; K-Selectride®; K-Selectride; KS-Selectride; L-Selectride® (Note: L-Selectride is lithium tri-sec-butylborohydride, a related but distinct compound); Potassium tris(butan-2-yl)boranuide
EINECS	Contact for details

Quality Control

Our Ks-Selectride® is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high performance. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, concentration, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C (refrigerated) to maintain stability and potency. The solution is highly volatile, easily oxidized, and reacts violently with water and protic solvents. Handle and store away from heat, sparks, open flame, and strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to slightly yellow solution
Concentration (in THF)	1.0 M
Assay (Titration)	≥ 95.0%
Identification (IR)	Conforms to standard
Water Content (KF)	≤ 0.1%
Peroxide (as H₂O₂)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.