Description

(1S,βs)-1,2,3,4,4Aα,4B,5,6,7,8,8Aα,9-Dodecahydro-2β,β-Dihydroxy-1-Hydroxymethyl-1,4Bβ,7-Trimethyl-7β-Phenanthreneethanol is a high-purity, complex diterpenoid derivative with a defined stereochemistry, valued for its role as a critical synthetic intermediate and reference standard. This compound matters for its utility in advanced organic synthesis, particularly in the construction of complex natural product analogs and pharmaceutical scaffolds. It is needed by research institutions, pharmaceutical development labs, and fine chemical manufacturers focused on steroid-like molecules, terpenoid chemistry, and novel therapeutic agent discovery.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates with steroidal or terpenoid backbones.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related compounds.
• Organic Synthesis Research: Serves as a sophisticated starting material or intermediate in academic and industrial research exploring complex polycyclic systems.
• Natural Product Analog Synthesis: Employed in the semi-synthesis or total synthesis of analogs of bioactive natural products derived from diterpenes.
• Process Chemistry Development: Used in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs) requiring this specific stereochemistry.

Basic Information

Product Name	(1S,βs)-1,2,3,4,4Aα,4B,5,6,7,8,8Aα,9-Dodecahydro-2β,β-Dihydroxy-1-Hydroxymethyl-1,4Bβ,7-Trimethyl-7β-Phenanthreneethanol
CAS No.	67911-60-8
Molecular Formula	C20H34O4
Molecular Weight	338.48 g/mol
Synonyms	7β-Phenanthreneethanol, dodecahydro derivative; (1S,4aS,4bR,7S,8aS)-1,2,3,4,4a,4b,5,6,7,8,8a,9-Dodecahydro-2,2-dihydroxy-1-(hydroxymethyl)-1,4b,7-trimethyl-7-phenanthreneethanol; 7β-Hydroxymethyl-1,4b-dimethyl-7-(1-hydroxy-1-methylethyl)-1,2,3,4,4a,4b,5,6,7,8,8a,9-dodecahydrophenanthrene-2,2-diol; A derivative of Totarol; Diterpenoid diol intermediate.
EINECS	Contact for details

Quality Control

Our (1S,βs)-1,2,3,4,4Aα,4B,5,6,7,8,8Aα,9-Dodecahydro-2β,β-Dihydroxy-1-Hydroxymethyl-1,4Bβ,7-Trimethyl-7β-Phenanthreneethanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.