Description

(4As)-2,3,4,4A,10,10Aα-Hexahydro-5,6,10α-Trihydroxy-7-[(R)-2-Hydroxy-1-Methylethyl]-1,1,4Aβ-Trimethylphenanthren-9(1H)-One is a complex, high-purity diterpenoid compound of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate stereochemistry and functional group array make it a valuable chiral building block and intermediate for developing novel bioactive molecules. This compound is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of steroids, terpenoids, and other complex natural product derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of novel therapeutic agents, particularly in steroid and terpenoid-based drug discovery.
• Advanced Organic Synthesis: Used as a sophisticated building block for constructing complex molecular architectures in academic and industrial research settings.
• Biochemical Research: Employed in studies investigating enzyme-substrate interactions, biosynthesis pathways of natural products, and structure-activity relationships (SAR).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in chromatographic analysis (HPLC, GC) within fine chemical production.
• Asymmetric Catalysis Research: Utilized as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.

Basic Information

Product Name	(4As)-2,3,4,4A,10,10Aα-Hexahydro-5,6,10α-Trihydroxy-7-[(R)-2-Hydroxy-1-Methylethyl]-1,1,4Aβ-Trimethylphenanthren-9(1H)-One
CAS No.	67895-41-4
Molecular Formula	C22H34O6
Molecular Weight	394.51 g/mol
Synonyms	7-[(1R)-2-Hydroxy-1-methylethyl]-2,3,4,4a,10,10aα-hexahydro-5,6,10α-trihydroxy-1,1,4aβ-trimethyl-9(1H)-phenanthrenone; 7-[(R)-2-Hydroxy-1-methylethyl]-2,3,4,4a,10,10aα-hexahydro-5,6,10α-trihydroxy-1,1,4aβ-trimethylphenanthren-9(1H)-one; 7-[(1R)-2-Hydroxy-1-methylethyl]-2,3,4,4a,10,10aα-hexahydro-5,6,10α-trihydroxy-1,1,4aβ-trimethyl-9(1H)-phenanthrenone (CAS 67895-41-4); Diterpenoid Intermediate 67895-41-4; CAS 67895-41-4
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and chiral purity is provided with every shipment, supporting your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.