Description

(Z)-6-Hydroxy-4-Methyl-4-Hexenoic Acid Methyl Ester is a specialized chiral intermediate featuring both hydroxyl and ester functional groups on an unsaturated carbon chain. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical sectors. Industries requiring high-purity chiral synthons for active pharmaceutical ingredients (APIs), fragrances, and advanced material research are the primary users of this material.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandins, leukotriene analogs, and other bioactive molecules.
• Fine Chemical Synthesis: Used in the production of complex natural product analogs and specialty chemicals requiring specific stereochemistry.
• Fragrance & Flavor Industry: Serves as a precursor for musk-like odorants and other aroma chemicals due to its structural framework.
• Agrochemical Research: Employed in developing chiral active ingredients for advanced pesticides and herbicides.
• Academic & R&D: A valuable reagent for methodological studies in asymmetric synthesis and organic chemistry research.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with tailored properties.

Basic Information

Product Name	(Z)-6-Hydroxy-4-Methyl-4-Hexenoic Acid Methyl Ester
CAS No.	67884-44-0
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	Methyl (Z)-6-Hydroxy-4-methyl-4-hexenoate; Methyl 6-Hydroxy-4-methyl-4-hexenoate (Z)-; (Z)-Methyl 6-Hydroxy-4-methylhex-4-enoate; 4-Hexenoic acid, 6-hydroxy-4-methyl-, methyl ester, (Z)-; 6-Hydroxy-4-methyl-4-hexenoic acid methyl ester, (Z)-; Methyl (Z)-6-hydroxy-4-methylhex-4-enoate
EINECS	Contact for details

Quality Control

Our (Z)-6-Hydroxy-4-Methyl-4-Hexenoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature and functional groups, it is recommended to handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% (Z)-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.