Description

Z-L-Ala-Chn2 is a protected amino acid derivative, specifically an N-benzyloxycarbonyl (Z) protected L-alanine building block. This compound is essential for the controlled synthesis of peptides and peptidomimetics, providing a crucial handle for orthogonal deprotection strategies in complex organic sequences. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and bioactive molecules.

Application

• Peptide Synthesis: A fundamental building block (Z-protected amino acid) for solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a key intermediate in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Used in the preparation of peptide-protein conjugates for diagnostic and therapeutic applications.
• Chemical Biology Research: Employed in the study of enzyme-substrate interactions and the development of enzyme inhibitors.
• Combinatorial Chemistry: A valuable reagent for generating diverse chemical libraries for high-throughput screening in drug discovery.
• Fine Chemical Production: Acts as a chiral synthon for the asymmetric synthesis of more complex organic molecules.

Basic Information

Product Name	Z-L-Ala-Chn2
CAS No.	67865-68-3
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	N-Carbobenzoxy-L-alanine; Z-L-Alanine; N-(Benzyloxycarbonyl)-L-alanine; (S)-2-((Benzyloxy)carbonylamino)propanoic acid; Cbz-L-Alanine; NSC 3349; L-Alanine, N-[(phenylmethoxy)carbonyl]-; Z-Ala-OH
EINECS	Contact for details

Quality Control

Our Z-L-Ala-Chn2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	-14.0° to -16.0° (c=1 in AcOH)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.