Description

Spiramycin Embonate is a macrolide antibiotic salt formed by combining spiramycin with embonic acid. This formulation is crucial for enhancing the stability and bioavailability of the active pharmaceutical ingredient, making it suitable for various therapeutic formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of veterinary and, in some regions, human antibiotic treatments targeting Gram-positive bacteria and mycoplasmas.

Application

• Veterinary Pharmaceutical Ingredient: Key active component in medicated feeds, premixes, and injectables for the treatment of respiratory and enteric infections in livestock and poultry.
• Human Pharmaceutical Research: Used in R&D for developing oral dosage forms, particularly where enhanced stability of the antibiotic is required.
• Antibiotic Intermediate: Serves as a critical intermediate in the synthesis of other spiramycin-based pharmaceutical compounds.
• Microbiological Studies: Employed as a reference standard in antimicrobial susceptibility testing and pharmacological research.
• Feed Additive Production: Incorporated into growth-promoting and prophylactic feed additives for animal health management.

Basic Information

Product Name	Spiramycin Embonate
CAS No.	67724-08-7
Molecular Formula	C₉₀H₁₄₈N₄O₂₀ • C₂₃H₁₆O₆
Molecular Weight	~ 1806.1 g/mol (for spiramycin base + embonate)
Synonyms	Spiramycin Pamoate; Spiramycin Embonate Salt; Foromacidin Pamoate; Sequamycin Embonate; Rovamycin Pamoate; Spiramycin 4,4'-Methylenebis(3-hydroxy-2-naphthoate); Spiramycin Pamoic Acid Salt
EINECS	Contact for details

Quality Control

Our Spiramycin Embonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, potency, and impurity profiles. We can support compliance with various pharmacopoeial standards (e.g., EP, USP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Microbial Limits	Meets EP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.