Description

2-Formyl-3-Hydroxy-A(1)-Norlup-20(29)-En-28-Oic Acid Methyl Ester is a high-purity, semi-synthetic triterpenoid derivative, serving as a critical advanced intermediate in pharmaceutical research and synthesis. Its value lies in providing a functionalized scaffold for the development of novel bioactive compounds, particularly in medicinal chemistry. This product is essential for R&D scientists and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality building blocks for drug discovery programs targeting inflammation, metabolic disorders, and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel lupane-based therapeutic agents.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Reference Standard: Serves as an analytical standard for quality control and method development in laboratories analyzing triterpenoid compounds.
• Academic & Industrial R&D: Employed in exploratory synthesis for creating new chemical entities (NCEs) with potential anti-inflammatory, antiviral, or anticancer activity.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for complex natural product derivatives.

Basic Information

Product Name	2-Formyl-3-Hydroxy-A(1)-Norlup-20(29)-En-28-Oic Acid Methyl Ester
CAS No.	67594-78-9
Molecular Formula	C₃₁H₄₆O₅
Molecular Weight	498.70 g/mol
Synonyms	Methyl 2-Formyl-3-hydroxy-A(1)-norlup-20(29)-en-28-oate; 3β-Hydroxy-2β-formyl-A(1)-norlup-20(29)-en-28-oic Acid Methyl Ester; Betulinic Aldehyde Derivative; Lup-20(29)-en-28-oic Acid, 2-formyl-3-hydroxy-A(1)-nor-, Methyl Ester; (3β)-2-Formyl-3-hydroxy-A(1)-norlup-20(29)-en-28-oic Acid Methyl Ester; 2-Formyl-3-hydroxy-1-norlup-20(29)-en-28-oic Acid Methyl Ester; Betulin Derivative Intermediate
EINECS	Contact for details

Quality Control

Our 2-Formyl-3-Hydroxy-A(1)-Norlup-20(29)-En-28-Oic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.