Description

Bromomethyl(Methyl)Malonic Acid Bis(1,1-Dimethylethyl) Ester is a high-value, protected malonic acid derivative that serves as a critical synthetic building block in advanced organic synthesis. Its primary commercial value lies in its role as a versatile precursor for the controlled introduction of functionalized methylene groups, enabling the construction of complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), novel crop protection agents, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly in constructing specific carbon frameworks found in APIs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its functional groups allow for precise structural modifications.
• Peptide Mimetics & Modified Amino Acids: Serves as a precursor for creating non-natural amino acids and peptidomimetics for medicinal chemistry and biochemical research.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Ligand & Catalyst Development: Utilized in the synthesis of complex organic ligands for metal catalysis and asymmetric synthesis.
• Chemical Research & Development: A versatile reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	Bromomethyl(Methyl)Malonic Acid Bis(1,1-Dimethylethyl) Ester
CAS No.	67587-04-6
Molecular Formula	C13H23BrO4
Molecular Weight	323.23 g/mol
Synonyms	Di-tert-butyl 2-(bromomethyl)-2-methylmalonate; 2-(Bromomethyl)-2-methylpropanedioic Acid Di-tert-butyl Ester; Bromomethylmethylmalonic Acid Di-tert-butyl Ester; tert-Butyl Bromomethyl(methyl)malonate; Di-tert-butyl Bromomethyl(methyl)malonate; (Bromomethyl)(methyl)propanedioic Acid Bis(1,1-dimethylethyl) Ester; 1,1-Dimethylethyl (Bromomethyl)(methyl)propanedioate (2:1)
EINECS	Contact for details

Quality Control

Our production of Bromomethyl(Methyl)Malonic Acid Bis(1,1-Dimethylethyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.