Description

Isobutylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it ideal for handling, storage, and controlled reactivity in sensitive transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key building block for constructing complex molecules via cross-coupling reactions.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental building block for introducing the isobutyl group into biaryl and heterobiaryl structures, which are core scaffolds in many active pharmaceutical ingredients (APIs) and agrochemicals.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of drug candidates, particularly in creating carbon-carbon bonds under mild, functional-group-tolerant conditions.
• Agrochemical Active Ingredient Development: Employed to synthesize novel herbicides, fungicides, and insecticides that require specific alkyl substitutions for optimal bioactivity.
• Material Science and OLED Research: Acts as a precursor for creating organic electronic materials, where the pinacol ester group offers improved solubility and processing stability.
• Chemical Biology and Probe Development: Useful for tagging biomolecules or creating molecular probes due to the selective reactivity of the boronate ester functionality.
• Catalyst and Ligand Synthesis: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	Isobutylboronic Acid Pinacol Ester
CAS No.	67562-20-3
Molecular Formula	C10H21BO2
Molecular Weight	184.09 g/mol
Synonyms	2-(2-Methylpropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Isobutylboronic Acid Pinacol Ester; Pinacol Isobutylboronate; (2-Methylpropyl)boronic Acid Pinacol Ester; Isobutyl-Bpin; B-Isobutyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(2-methylpropyl)-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Isobutylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production applications. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.