Description

1-(5-Amino-2-Fluorophenyl)Ethanone is a high-purity fluorinated aromatic ketone intermediate, valued for its reactive amino and carbonyl functional groups. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its specific substitution pattern enables targeted chemical transformations. It is primarily sought by research and development chemists and process engineers in fine chemical manufacturing for creating active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where the fluorine moiety imparts unique electronic and surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and fluorinated aromatic systems.
• Dye and Pigment Intermediate: Utilized in the development of specialty colorants and imaging agents.

Basic Information

Product Name	1-(5-Amino-2-Fluorophenyl)Ethanone
CAS No.	67500-19-0
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	5'-Amino-2'-fluoroacetophenone; 2'-Fluoro-5'-aminoacetophenone; 1-(5-Amino-2-fluorophenyl)ethan-1-one; 2-Fluoro-5-aminoacetophenone; 5-Amino-2-fluoroacetophenone; 1-Acetyl-5-amino-2-fluorobenzene; Ethanone, 1-(5-amino-2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 1-(5-Amino-2-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.