Description

Diethyl 2-(1H-Pyrrol-1-Yl)Malonate is a high-purity, specialized malonate ester derivative that serves as a critical building block in advanced organic synthesis. Its unique pyrrole-substituted structure makes it a valuable precursor for constructing complex heterocyclic frameworks and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with targeted properties.

Application

• Pharmaceutical Intermediates: Key synthon for the synthesis of pyrrole-containing drug candidates, including potential kinase inhibitors and central nervous system (CNS) active agents.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with heterocyclic cores for enhanced efficacy.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and development of electron-transport materials and emissive layer components for display technologies.
• Coordination Chemistry & Ligand Design: Serves as a precursor for polydentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A versatile reagent for methodology development and constructing complex molecular architectures in medicinal and synthetic chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	Diethyl 2-(1H-Pyrrol-1-Yl)Malonate
CAS No.	67451-43-8
Molecular Formula	C11H15NO4
Molecular Weight	225.24 g/mol
Synonyms	Diethyl (1H-pyrrol-1-yl)malonate; 1H-Pyrrole-1-malonic Acid Diethyl Ester; Diethyl 1H-Pyrrole-1-malonate; 2-(1H-Pyrrol-1-yl)malonic Acid Diethyl Ester; Malonic Acid, (1-Pyrrolyl)-, Diethyl Ester; Diethyl (1-pyrrolyl)malonate; Pyrrole-1-malonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 2-(1H-Pyrrol-1-Yl)Malonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.