Description

Phenol, 4-(2-Mercaptoethyl)- is a specialized phenolic thiol compound that serves as a versatile building block and functional additive in advanced chemical synthesis. Its unique structure, featuring both a phenolic hydroxyl group and a thiol (mercapto) moiety, makes it valuable for introducing specific reactivity and properties into target molecules. This compound is primarily sought by researchers and manufacturers in the pharmaceutical, polymer, and specialty chemical industries for applications requiring precise molecular design and functionalization.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring thiol or phenolic functionalities for bioactivity or as a conjugation site.
• Polymer Modification & Cross-linking Agent: Acts as a chain transfer agent or cross-linker in the production of specialty polymers, resins, and adhesives, enhancing properties like thermal stability and mechanical strength.
• Ligand Synthesis for Catalysis: Employed in the preparation of chelating ligands for metal catalysts used in asymmetric synthesis and other organic transformations.
• Surface Functionalization: Used to modify material surfaces (e.g., gold nanoparticles, polymers) via the thiol group, creating platforms for sensors, coatings, and biomaterials.
• Antioxidant Precursor: Serves as a key intermediate in the synthesis of complex phenolic antioxidants for stabilizing fuels, lubricants, and plastics.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new organic reactions and developing novel chemical entities.

Basic Information

Product Name	Phenol, 4-(2-Mercaptoethyl)-
CAS No.	67382-72-3
Molecular Formula	C8H10OS
Molecular Weight	154.23 g/mol
Synonyms	4-(2-Mercaptoethyl)phenol; 2-(4-Hydroxyphenyl)ethanethiol; 4-Hydroxy-2-phenylethanethiol; p-(2-Mercaptoethyl)phenol; 2-(4-Hydroxyphenyl)ethyl mercaptan; (4-Hydroxyphenyl)ethanethiol; Thio-Tyrosol; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Phenol, 4-(2-Mercaptoethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets precise customer specifications and high-purity standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its sensitivity to oxidation, the container should be kept sealed and only opened under controlled conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.