Description

6-[(p-Tolylsulfonyl)Amino]Hexanoic Acid Methyl Ester CAS NO 67370-67-6 is a high-purity, protected amino acid derivative featuring a tosyl-protected amine and a methyl ester group. This compound serves as a critical building block and intermediate in advanced organic synthesis, offering controlled reactivity for the construction of complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel active ingredients and specialty compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of peptide mimetics, enzyme inhibitors, and other bioactive molecules.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative for introducing specific functional groups.
• Organic Synthesis Building Block: Employed in the preparation of complex organic scaffolds, including heterocycles and macrocycles, due to its reactive ester and protected amine functionalities.
• Chemical Research & Development: Serves as a standard or starting material in medicinal chemistry programs and process development for new chemical entities.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, including dyes, liquid crystals, and advanced polymer precursors.
• Bioconjugation: Potential use in linker chemistry for attaching molecules to proteins, surfaces, or other biomolecules.

Basic Information

Product Name	6-[(p-Tolylsulfonyl)Amino]Hexanoic Acid Methyl Ester
CAS No.	67370-67-6
Molecular Formula	C15H23NO4S
Molecular Weight	313.41 g/mol
Synonyms	Methyl 6-[(4-methylphenyl)sulfonyl]amino]hexanoate; Methyl 6-(p-toluenesulfonamido)hexanoate; 6-(Tosylamino)hexanoic Acid Methyl Ester; N-(p-Tolylsulfonyl)-6-aminohexanoic Acid Methyl Ester; Methyl N-(p-toluenesulfonyl)-6-aminohexanoate; 6-[(4-Methylbenzenesulfonyl)amino]hexanoic acid methyl ester; Tosyl-6-Ahx-OMe; 6-(p-Toluenesulfonylamino)caproic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 6-[(p-Tolylsulfonyl)Amino]Hexanoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.