Description

1,2-o-Dihexadecyl-Sn-Glycerol is a synthetic, high-purity glycerol derivative with a defined stereochemistry at the Sn position. This compound serves as a critical lipid intermediate and building block for advanced chemical synthesis. It is essential for researchers and manufacturers in the pharmaceutical, cosmetic, and specialty chemical industries requiring precise molecular structures for product development.

Application

• Lipid Nanoparticle (LNP) Formulation: A key structural component in the synthesis of ionizable cationic lipids for mRNA vaccine and therapeutic delivery systems.
• Pharmaceutical Intermediates: Used in the synthesis of prodrugs, phospholipid analogs, and other bioactive lipid molecules.
• Cosmetic Ingredient Synthesis: Acts as a lipophilic backbone for creating emollients, emulsifiers, and skin-conditioning agents in high-end skincare products.
• Biomimetic Membrane Research: Employed in the construction of model membranes and liposomes for biophysical studies and drug encapsulation.
• Surfactant & Detergent Chemistry: Serves as a precursor for non-ionic surfactants with specific branching and hydrophobicity.
• Chemical Biology Probes: Utilized to create labeled lipids for tracking cellular uptake and metabolic pathways.

Basic Information

Product Name	1,2-o-Dihexadecyl-Sn-Glycerol
CAS No.	67337-03-5
Molecular Formula	C35H72O3
Molecular Weight	540.95 g/mol
Synonyms	1,2-Di-O-hexadecyl-sn-glycerol; sn-1,2-Dihexadecylglycerol; 1,2-Dihexadecyl-rac-glycerol (related); Dihydroxy Dihexadecyl Ether Glycerol; 1,2-Di-O-cetyl-sn-glycerol; 3-Hydroxy-1,2-dihexadecoxypropane; Hexadecyl Glycerol Diether; Lipid A precursor analog (intermediate)
EINECS	Contact for details

Quality Control

Our 1,2-o-Dihexadecyl-Sn-Glycerol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters are available upon request, supporting compliance in GMP-aligned applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is stable under inert atmosphere. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.