Description

(1R)-(+)-Camphanic Acid CAS NO 67111-66-4 is a high-purity, enantiomerically pure chiral auxiliary and derivatizing agent derived from camphor. Its value lies in its ability to resolve racemic mixtures of alcohols and amines, a critical step in the synthesis of single-enantiomer pharmaceuticals and fine chemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors where stereochemical purity is paramount.

Application

• Chiral Resolution Agent: Key for the separation of enantiomers of alcohols, amines, and amino acids via diastereomeric salt formation or esterification.
• Pharmaceutical Intermediate: Used in the asymmetric synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Analytical Chemistry: Employed as a derivatizing agent in HPLC and GC to separate and quantify enantiomeric compounds.
• Agrochemical Synthesis: Facilitates the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A fundamental tool in methodological development for asymmetric synthesis and catalysis studies.
• Fine Chemical Production: Used in the manufacture of specialty flavors, fragrances, and advanced organic materials.

Basic Information

Product Name	(1R)-(+)-Camphanic Acid
CAS No.	67111-66-4
Molecular Formula	C10H14O4
Molecular Weight	198.22 g/mol
Synonyms	(1R)-(+)-Camphanic Acid; (1R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride; D-(+)-Camphanic Acid; (+)-Camphanic Acid; (1R)-Camphanic Acid; Camphanic Acid, (1R)-; Camphanic Acid, (+)-; (1R,4S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Our (1R)-(+)-Camphanic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), optical rotation, and identity confirmation (IR, NMR) to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Optical Rotation [α]D20	+18.0° to +22.0° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.