Description

3-Phenyl-4'-Trifluoromethylpropiophenone is a high-value fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a versatile building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that require this product include pharmaceutical R&D for creating novel active ingredients, agrochemical manufacturers for developing new crop protection agents, and specialty chemical producers for synthesizing advanced materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for advanced fluorinated liquid crystals used in high-performance displays (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for OLED devices due to its favorable electronic properties.
• Advanced Material Research: Utilized in academic and industrial R&D for creating novel polymers and specialty chemicals with unique properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.

Basic Information

Product Name	3-Phenyl-4'-Trifluoromethylpropiophenone
CAS No.	67082-00-2
Molecular Formula	C16H13F3O
Molecular Weight	278.27 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3-phenyl-1-propanone; 3-Phenyl-1-[4-(trifluoromethyl)phenyl]-1-propanone; 4'-Trifluoromethyl-3-phenylpropiophenone; 3-Phenyl-4'-(trifluoromethyl)propiophenone; Propiophenone, 3-phenyl-4'-(trifluoromethyl)-; 67082-00-2; 3-Phenyl-4'-trifluoromethyl propiophenone
EINECS	Contact for details

Quality Control

Our 3-Phenyl-4'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent quality suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our production adheres to cGMP principles where applicable, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.