Description

1,2-Cyclohexanediol, 4-(1,1-Dimethylethyl)- is a versatile, high-purity diol derivative of cyclohexane, distinguished by the presence of a tert-butyl group which imparts unique steric and electronic properties. This compound is valued for its role as a key chiral building block and intermediate in the synthesis of complex organic molecules, offering significant utility in advanced research and development. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis, ligand development, and the production of high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Ligand & Catalyst Preparation: Acts as a precursor for chiral ligands and organocatalysts used in enantioselective transformations, such as hydrogenation and oxidation reactions.
• Polymer & Resin Modification: Incorporated into specialty polymers, epoxy resins, and polyurethanes to modify physical properties like flexibility, adhesion, and chemical resistance.
• Flavor & Fragrance Chemistry: Utilized in the synthesis of complex aroma chemicals and fragrance ingredients due to its cyclic structure and functional groups.
• Research & Development: A valuable standard and reagent in academic and industrial R&D labs for exploring new synthetic methodologies and material science.

Basic Information

Item	Detail
Product Name	1,2-Cyclohexanediol, 4-(1,1-Dimethylethyl)-
CAS No.	67027-80-9
Molecular Formula	C10H20O2
Molecular Weight	172.26 g/mol
Synonyms	4-tert-Butyl-1,2-cyclohexanediol; 4-(tert-Butyl)cyclohexane-1,2-diol; 4-(1,1-Dimethylethyl)-1,2-cyclohexanediol; 4-tert-Butylcyclohexane-1,2-diol; 1,2-Dihydroxy-4-tert-butylcyclohexane; 4-tert-Butyl-1,2-dihydroxycyclohexane; 4-(tert-Butyl)-1,2-cyclohexanediol
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanediol, 4-(1,1-Dimethylethyl)- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters such as assay, enantiomeric excess (where applicable), and impurity profiles are provided and available upon request. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.