Description

(-)-trans-2-tert-Butylcyclohexanol CAS NO 13492-07-4 is a high-purity, stereochemically defined chiral alcohol of significant importance in advanced organic synthesis. Its rigid, bulky structure makes it a valuable chiral auxiliary, resolving agent, and building block for the preparation of complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control in their synthetic processes.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Utilized to induce stereoselectivity in key bond-forming reactions.
• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of active pharmaceutical ingredients (APIs) with specific stereochemistry.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where biological activity is stereospecific.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands used in transition metal catalysis.
• Flavor and Fragrance Industry: Employed in the synthesis of enantiomerically pure aroma chemicals.
• Material Science Research: Investigated as a monomer or modifier for creating polymers with chiral properties.
• Analytical Standard: Provides a reference standard for chromatographic and spectroscopic methods.

Basic Information

Product Name	(-)-trans-2-tert-Butylcyclohexanol
CAS No.	13492-07-4
Molecular Formula	C₁₀H₂₀O
Molecular Weight	156.27 g/mol
Synonyms	(-)-trans-2-(1,1-Dimethylethyl)cyclohexanol; (1R,2R)-2-tert-Butylcyclohexanol; trans-(-)-2-tert-Butylcyclohexanol; (R,R)-2-tert-Butylcyclohexanol; 2-tert-Butylcyclohexanol, trans-(-)-; L-(-)-trans-2-tert-Butylcyclohexanol; (-)-TBC; trans-2-(tert-Butyl)cyclohexanol, (-)-form
EINECS	Contact for details

Quality Control

Our (-)-trans-2-tert-Butylcyclohexanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.